Alison Patteson

Alison Patteson
Assistant Professor\Physics Department

Research
Soft matter, Biomechanics, Microfluidics, Active matter, Cell motility

Address: 229-C Physics Building
Email: aepattes at syr dot edu
Website: https://aepattes.expressions.syr.edu/

Immunofluorescence image of mouse embryo fibroblasts showing DNA (blue), actin (red), and vimentin intermediate filaments (green), which form a perinuclear cage.

Research Interests
Alison’s research interests include problems in cell motility and active living matter. Her research aims to identify how cells navigate and respond to the physical features of their environment (mechanical properties, presence of boundaries, and cell-cell contacts) to achieve important biological functions, such as cancer metastasis, wound healing, and biofilm formation. Her research program employs microfluidic technology, single-molecule experiments, knock-out cell models, and concepts from non-equilibrium statistical physics to investigate the dynamics of swimming bacteria and mammalian cell motility. Recent research contributions include identifying novel functions of vimentin intermediate filaments in securing the mechanical stability of the nucleus, as well as developing new models of active fluids flows generated by swimming bacterial suspensions, which was awarded the American Physical Society Statistical and Nonlinear Physics Dissertation Award.

List of 5 publications

A.E. Patteson, K. Pogoda, F.J. Byfield, E.E. Charrier, P.A. Galie, P. Deptula, R. Bucki, and P.A. Janmey, Loss of vimentin intermediate filaments decreases peri-nuclear stiffness and enhances cell motility through confined spaces. (In review.) arXiv:1807.06378

A.E. Patteson, A. Gopinath, and P.E. Arratia, The propagation of active-passive interfaces in bacterial swarms. Nature Communications, 9, 5373 (2018). arXiv:1805.06429

A.E. Patteson*, A. Gopinath*, and P. E. Arratia. Active colloids in complex fluids. Current Opinion in Colloid & Interface Science. 21 86-96, arXiv:1602.02693 (2016).

A. E. Patteson, A. Gopinath, P. K. Purhot, and P. E. Arratia. Particle diffusion in active fluids is non-monotonic in size. Soft Matter. 12 2365, arXiv:1505:05803 (2016)

A.E. Patteson, A. Gopinath, M. Goulian, and P. E. Arratia. Running and tumbling with E. coli in polymeric solutions. Scientific Reports 5 15761, arXiv:1511.00708 (2015).

*Denote equal contribution

Teaching Interests
Vibrations, Waves, and Optics; Biophysics

Short Bio
Alison Patteson received her B.S. in Physics and Mathematics in 2011 from Kutztown University of Pennsylvania. She received her Ph.D. in Mechanical Engineering in 2016 from University of Pennsylvania, where she was advised by Professor Paulo Arratia. Her thesis work involved experimental investigations of complex flows generated by swimming bacteria. Support for her Ph.D. was provided by a National Science Foundation graduate research fellowship. Alison was a postdoctoral researcher at the Perelman School of Medicine at the University of Pennsylvania, working with Professor Paul Janmey to study the biomechanics of vimentin intermediate filaments at the cellular level. Alison joined the Department of Physics at Syracuse University as an Assistant Professor in 2010. Her current research interests include problems in cell motility and active living matter.

 

Comments are closed.