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Henderson Research Group Contact Information Website: http://henderson.syr.edu Email: jhhender@syr.edu Research Interests
Henderson Laboratory Facilities Cell and Tissue Culture Core Cell and tissue cultures are an important component of many research areas being investigated by Institute faculty. The capabilities of the Cell and Tissue Culture Core include: standard and hypoxic (low oxygen) cell and tissue culture; cryogenic cell storage; microdissection; mechanostimulation; and tissue harvest and primary cell isolation. Molecular Biology Core Modern molecular biology provides many powerful tools that can be used to analyze cells and tissues being investigated in biomaterials and tissue engineering research. The capabilities of the Molecular Biology Core include: cell and tissue homogenization; RNA/DNA isolation and analysis; gene expression analysis (real-time PCR); gel electrophoresis; and spectrophotometric analysis. Morphology Core This facility houses instrumentation used for all of the morphological studies associated with Institute research activities. The capabilities of the Morphology Core include: embedding and sectioning of hard and soft tissues; histochemical and immunohistochemical staining; and brightfield, phase, and fluroescence microscopy. Sample Publications 1. Henderson, J. H., Welter, J. F., Mansour, J. M., Niyibizi, C., Caplan, A. I., and Dennis, J. E. Cartilage tissue engineering for laryngotracheal reconstruction: comparison of chondrocytes from three anatomic locations in the rabbit. Tissue Eng, 13:843-853, 2007. doi:10.1089/ten.2006.0256 2. Henderson, J. H., de la Fuente, L., Romero, D., Colnot, C. I., Huang, S., Carter, D. R., and Helms, J. A. Rapid growth of cartilage rudiments may generate perichondrial structures by mechanical induction. Biomechan Model Mechanobiol, 6:127-137, 2007. doi:10.1007/s10237-006-0038-x 3. Henderson, J. H., Chang, L. Y., Song, H. M., Longaker, M. T., and Carter, D. R. Age-dependent properties and quasi-static strains in the rat sagittal suture. J Biomechanics, 38:2294-2301, 2005. doi:10.1016/j.jbiomech.2004.07.037 4. Henderson, J. H., Longaker, M. T., and Carter, D. R. Sutural bone deposition rate and strain magnitude during cranial development. Bone, 34:271-280; 2004. doi:10.1016/j.bone.2003.10.007 5. Henderson, J. H., and Carter, D. R. Mechanical induction in limb morphogenesis: the role of growth-generated strains and pressures. Bone, 31:645-653; 2002. doi:10.1016/S8756-3282(02)00911-0 Return to Research |
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