SBI Research Facilities

SBI Central Research Facility is located in Bowne Hall (4th Floor)

The Central Research Facilities of the Syracuse Biomaterials Institute at Syracuse University encompasses approximately 15,000 square feet of multiuser space.

Polymer Synthesis and Molecular/Solution Characterization Lab includes glassware based synthesis apparatus to enable standard organic reactions and polymerizations and processing equipment for electrospinning, extrusion, compression-molding, micro-embossing and polymer sheet and film preparation. This lab also includes instrumentation for the determination of polymer molecular weight distribution by GPC/light scattering and molecular identity by HPLC.

Thermal Analysis Lab houses state of the art thermal analysis instrumentation to probe polymeric thermal stability and weight loss by thermogravimetric analysis (TGA) and melting and glass transition temperatures by differential scanning calorimetry (DSC).

Materials Physical Characterization Lab includes instrumentation to measure polymer viscoelasticity by dynamic mechanical analysis (DMA) and rotational rheometry. Characterization of polymer thin coating adsorption, desorption and degradation are made possible with a quartz crystal microbalance outfitted with a flow-through fluid cell. This lab also includes potensiostats, a hydraulic testing apparatus with a biaxial servohydraulic mechanical testing frame, a custom-built indentation system for microindentation of soft, hydrated polymers and biological materials and a rotational viscometer.

Optics Lab includes digital light microscopy capabilities built around polarizing and stereo microscopes and a high-resolution CCD camera, augmented by a heating/cooling stage and a temperature-controlled tensile tester that can be used to test samples while simultaneously imaging to observe flow-modified microstructures. A spectrometer which mounts on the microscopes is also available.

Microstructure Lab includes a SAXS/WAXD system capable of rapid assessment of polymer and composite microstructure in the range 0.15 – 200 nm.

Material Morphology Labs include instrumentation for analyzing the morphology and surface chemistry of materials studied in the SBI labs. Within this lab are a Fourier transform infrared spectrometer with AutoImage FTIR microscope. A scanning electron microscope (SEM) fitted with an energy dispersive spectroscopy (EDS) system allows for SEM imaging and elemental analysis. A digital 3D microscope is capable of imaging material surfaces at high resolution without the need for gold coating or vacuum. This lab houses a transmission electron microscope (TEM) and equipment for ultracryomicrotomy. An atomic force microscope (AFM) with an “E”scanner facilitates imaging to nearly atomic levels and is enhanced by a TS-75 Triboscope which allows for nanomechanical testing of material surfaces through indentation. Finally, this lab houses a contact angle goniometer for the assessment of material surface hydrophobicity.

Tissue Culture Labhouses facilities for culturing cells of animal and human origin under biosafety level 2 conditions. Included are incubators, flow cells, biosafety cabinets and a Flexcell system for applying mechanical stimulation to cultures. There are also several inverted-fluorescence microscopes for the observation of cells on materials, including time-lapse imaging.

Microbiology Lab includes facilities to study the interactions between bacteria and materials.

Molecular Biology Labincludes DNA electrophoresis systems, protein electrophoresis and blotting systems, thermocyclers including real-time PCR machines, a microplate reader, and a Luminex® for multiplex immunoassays.

Nanomanufacturing and 3D Printing Labs will house several platforms for the development of hierarchial 3D biopolymers with a targeted architecture using 3D printers at millimeter and micrometer scales as well as multiphoton-assisted projection stereolithography (MAPs).

 

SBI researchers have access to other analytical instruments located outside of the Central Research Facilities. These include, but are not limited to: laser-scanning confocal microscopy (SU Department of Biology), surface profilometry (SU Department of Physics), Fluorescence–activated cell sorting (FACS, SU Biomedical and Chemical Engineering), Nuclear Magnetic Resonance Spectroscopy (NMR, SU Department of Chemistry and SUNY ESF), Gas Chromatography/Mass Spectrometry (GC/MS, SUNY ESF), N.C. Brown Center for Ultrastructure Studies (SUNY ESF) and Microcomputed tomography (Micro CT, SUNY Upstate Medical University).

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Item Location Contact
Modulated DSC with refrigerated cooling
TA Instruments Q100 DSC
Bowne 4th floor Prof. Patrick Mather
Thermogravimetric Analysis
TA Instruments Q500
 Bowne 4th floor Prof. Patrick Mather
Rheometer
Anton Paar MCR501
Bowne 4th floor  Prof. Patrick Mather
Quartz Crystal Microbalance
SRS QCM200
 Bowne 4th floor Prof. Patrick Mather
Polarizing Microscope with optical microrheometer, heating/cooling stage, shear cell, spectrographic birefringence apparatus, and Mito CCD attachments
Olympus BX-51
Bowne 4th floor  Prof. Patrick Mather
Electrospinning apparatus
Custom Built
Bowne 4th floor Prof. Patrick Mather
Incubator Shakers
New Brunswick C24
Bowne 4th floor Prof. Patrick Mather
E-beam Evaporator (Ti, Au only)
Thermionics VE-100
 CST 3-036 Prof. Yan-Yeung Luk
Ellipsometer(discrete wavelength ellipsometer room) CST 4-041 Prof. Yan-Yeung Luk
Water Purification System
Millipore RiOs 5 and Milli-Q Biocel A-10
 CST 4-041 Prof. Yan-Yeung Luk
Polarizing Microscope
Olympus BX-51
CST 3-036 Prof. Yan-Yeung Luk
Potensiostat
Pine Model AFCBP1
 CST 3-036 Prof. Yan-Yeung Luk
Labconco purifier vertical clean bench
Laminar hood
CST 3-036 Prof. Yan-Yeung Luk
Cryogenic Storage System
VWR CryoPro BR-1
CST 3-036 Prof. Yan-Yeung Luk
Inverted Microscope
Motic AE-31
CST 3-036 Prof. Yan-Yeung Luk
Scanning Electron Microscope with X-ray Spectrophotometer
Joel 5600
Bowne 4th floor Prof. Patrick Mather
Atomic Force Microscope with Electrochemical Attachment and Nanoindentation Capabilityg Bowne 4th floor Prof. Jeremy Gilbert
Digital Instruments Nanoscope III  Bowne 4th floor Prof. Patrick Mather
Hydraulic testing apparatus with 8500-Plus panel control and computer-controlled custom data collection
Instron 1350
 Bowne 4th floor Prof. Patrick Mather
Fourier Transform Infrared Spectrometer with AutoImage FTIR Microscope
Perkin-Elmer Spectrum One
Bowne 4th floor Prof. Jeremy Gilbert
Differential scanning calorimeter
Perkin-Elmer Pyris 1
 Bowne 4th floor Prof. Patrick Mather
Inverted Fluorescence Microscope and Imaging System
Zeiss Axiovert 40 CFL with Phase Contrast
Bowne 4th floor Prof. Patrick Mather
Custom built indentation system for microindentation of soft, hydrated polymers and biological materials  Bowne 4th floor Prof. Jeremy Gilbert
Rotational Viscometer
Brookfield DV-E
 Bowne 4th floor Prof. Patrick Mather
MicroCT Scanner
Scanco 40
SUNY Upstate Prof. Kenneth Mann
Biaxial Servohydraulic Mechanical Test Frame
MTS Bionix
 SUNY Upstate Prof. Kenneth Mann
Fatigue crack growth measurement equipment
Fractomat/KrakGage
SUNY Upstate Prof. Kenneth Mann
Surface Profilometer
Mitutoyo 178-923
 SUNY Upstate Prof. Kenneth Mann
Viscometer with small sample adaptor
Brookfield
 SUNY Upstate Prof. Kenneth Mann
SUN and PC Workstations with FEA Modeling and Medical Imaging Software
PATRAN, MARC, NASTRAN and MIMICS
 SUNY Upstate Prof. Kenneth Mann
Digital Image Correlation System (2-D) with Spot RT Camera
RapidCorrelator
 SUNY Upstate Prof. Kenneth Mann
Florescence Microscope with Motorized Z-Drive and Deconvolution Software.
ZEISS AXIO IMAGER MOT M1
 445 Link Hall  Prof. Dacheng Ren
DNA and Protein Electrophoresis Systems  445 Link Hall  Prof. Dacheng Ren
Western Blot System  445 Link Hall  Prof. Dacheng Ren
Spectrophotometer
Gensys 5
 445 Link Hall  Prof. Dacheng Ren
Microplate reader
FLx800, Bio-Tek Instruments, Inc.
 445 Link Hall  Prof. Dacheng Ren
Microcentrifuge Machines
5415D & 5415R, Eppendorf
 445 Link Hall  Prof. Dacheng Ren
Micropulser Electroporator
FLx800, Bio-Tek Instruments, Inc.
 445 Link Hall  Prof. Dacheng Ren
Luminometer
20/20n, Turner Design
 445 Link Hall  Prof. Dacheng Ren
Biofilm Flow Chamber Systems  445 Link Hall  Prof. Dacheng Ren

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