James Dabrowiak

James Dabrowiak
Professor,
Department of Chemistry

Address: 2-016D Center Science & Technology
Phone: 315-443-4601
E-mail: jcdabrow@syr.edu

Website: http://asfaculty.syr.edu/pages/chem/Dabrowiak-James.html

Research

Mechanism of anticancer drug action, anticancer drug delivery, drug nucleic acid interactions, pathogen detection using sensors, metals in medicine.

Recent Publications

Cytotoxicity of mesoporous silica nanoparticles. Anthony J. Di Pasqua, Krishna K. Sharma, Yan-Li Shi, Bonnie B. Toms, Wayne Ouellette, James C. Dabrowiak*, Tewodoros Asefa*, J. Inorg. Biochem., submitted.

Role of carbonate in the cytotoxicity of carboplatin. Anthony J. Di Pasqua, Jerry Goodisman, Deborah J. Kerwood, Boonie B. Toms, Ronald L. Dubowy, James C. Dabworiak*, Chem. Res. Toxicol., 2007, 20, 896-904.

The activation of platinum (II) antiproliferative drugs in carbonate medium by means of a DNA sensor. Mauro Ravera, Graziana Bagni, Marco Mascini, James C. Dabrowiak, Domenico Oscella, J. Inorg. Biochem., 2007, 101, 1023-27.

Modification of carboplatin by Jurkat cells. Anthony J. Di Pasqua, Jerry Goodisman, Deborah J. Kerwood, Boonie B. Toms, James C. Dabrowiak*, J. Inorg. Biochem., 2007, 101, 1438-1441.

Cisplatin carbonato complexes. Implications for uptake, antitumor properties, and toxicity. Corey R. Centerwall, Jerry Goodisman, Deborah J. Kerwood, James C. Dabrowiak*, J. Am. Chem. Soc., 2005, 127, 12769-69.

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